Cutaneous T-Cell Lymphoma Market Size is expected to be USD 1.6 Billion by 2025
12 Oct, 2017

Cutaneous T-cell lymphoma (CTCL) is a group of lympho proliferative disorders characterized by localization of neoplastic T lymphocytes to the skin. Collectively, CTCL is classified as a type of non-Hodgkin lymphoma (NHL). Cutaneous T-cell lymphomas (CTCL) are the most common types of skin lymphoma.  More than 3 out of every 4 skin lymphomas diagnosed are CTCLs. They often appear as eczema-like skin rashes and can affect widespread parts of the body. There are different subtypes of CTCL, mostly they are slow growing but some can be fast growing. The most common types of CTCL are Mycosis Fungoides and Sezary Syndrome

1. Mycosis fungoides (MF) is the most common type of Cutaneous T-Cell Lymphoma (CTCL). The disease looks different in each patient, with skin symptoms that can appear as patches, plaques, or tumors. Patches are usually flat, possibly scaly, and look like a rash; plaques are thicker, raised, usually itchy lesions that are often mistaken for eczema, psoriasis, or dermatitis; and tumors are raised bumps, which may or may not ulcerate.
2. Sezary syndrome is an advanced, variant form of mycosis fungoides, which is characterized by the presence of lymphoma cells in the blood. Extensive thin, red, itchy rashes usually cover over 80 percent of the body. About 1 in 20 people with CTCL (5%) have Sezary syndrome.

US Epidemiology Scenario –

• 3200 approx. Cases in 2016
• 1700  approx.  Cases of Mycosis Fungoides in 2016
• Men account for over 60% of total cases.

Market Forecast till 2025 –

We have seen that the United States accounts for the highest incident population of CTCL than EU5 (Germany, France, Spain, Italy and UK) and Japan. There were approximately 3200 incident cases in 2016. According to Diligent Market, it is estimated that the incident cases of CTCL shall increase at a CAGR of 0.35% for the period 2013-2025

In 2013, there were 1703 cases of Mycosis Fungoides estimated in United States. The incident rate of Mycosis fungoides has been increasing significantly since 1970s. Other subtypes includes Sezary syndrome, Primary Cutaneous Peripheral T-cell Lymphoma, unspecified, ATLL, Primary Cutaneous CD30+ T-cell Lympho Proliferative disorders and Subcutaneous Panniculitis-like T-cell Lymphoma (SPTCL), which comprises of approximately XX% cases of total CTCL incident population.

Complete Report with Detailed TOC and List of Figures @ https://www.diligentmarket.com/cutaneous-t-cell-lymphoma-ctcl-market-insights-epidemiology-and-market-forecast-2025-13702-p.php

Key Findings –

• 7 Major Market Size is expected to be USD 1.6 Billion by 2025
• United States contribute major shares to the CTCL market as compared to other Countries
• Early Stage Therapies [IA and IB] will fuel the growth of the market.
• Upcoming Drugs:  Mogamulizumab, Adcetris (Brentuximab Vedotin), E7777 and SGX301 will greatly impact the market size of CTCL

The treatment of CTCL depends on the disease stage. Early stage therapies are topical, including corticosteroids, retinoids, imiquimod (Aldara), ultraviolet A irradiation (PUVA), and total skin electron beam therapy. Systemic therapies are introduced in the advanced stages where the disease is widespread and/or resistant to topical treatment. These include interferon alpha injections, stem cell transplant, alemtuzumab (MabCampath) and other chemotherapy regimens. The FDA approved drugs are Istodax (romidepsin), Valchlor (mechlorethamine), Uvadex (methoxsalen), Targretin (bexarotene) and Zolinza (vorinostat).

Amongst all the 7MM, United States accounts for highest market share for CTCL due to high incidence as well as due to high annual cost of therapy. The total Cutaneous T-Cell Lymphoma market size in 7MM will increase at a compound annual growth rate (CAGR) of 1.6% for the forecasted period i.e., 2017-2025 and will reach 1.6 Billion by 2025

United States

Early stage accounts higher market share of CTCL in comparison to the late stage. According to Diligent Market, it is estimated that the market size of early stage and late stage CTCL shall increase at a CAGR of 1.89% and 0.93% respectively from 2013 to 2025.